("Aspartame"[supplementary concept] OR "Aspartame"[tw] OR " L-aspartyl-L- phenylalanine methyl ester "[tw] OR "22839-47-0"[EC/RN Number] OR "22839-47-0") AND (“Mutation”[Mesh] OR “Cytogenetic Analysis”[Mesh] OR “Mutagens”[Mesh] OR “Oncogenes”[Mesh] OR “Genetic Processes”[Mesh] OR "genomic instability"[MesH] OR chromosom* OR clastogen* OR “genetic toxicology” OR “strand break” OR “unscheduled DNA synthesis” OR “DNA damage” OR “DNA adducts” OR "SCE" OR "chromatid" OR micronucle* OR mutagen* OR "DNA repair" OR "UDS" OR "DNA fragmentation" OR "DNA cleavage")